North Wyke is an historic manor in the parish of South Tawton, Devon. The surviving grade I listed manor house, the original Devonshire seat of the Wyke family from the early 13th century to 1714, retains its basic mediaeval form, but was "improved and reconstructed" by Rev. William Wykes-Finch (d.1920) in 1904, historian and descendant of the Wyke family, to the design of G.H. Fellowes Prynne. Currently, the manor is part of Rothamsted Research's North Wyke site.